Clinical Trial: Nut Allergy Study: Double-blind Challenge and Oral Desensitization

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Nut Allergy Study: Improving Diagnosis And Treatment Of Nut Allergy

Brief Summary: Nut sensitization in skin prick tests is common in areas, including Finland, where birch pollen is abundant. However, sensitization to nuts in skin prick test does not predict the possibility of allergic symptoms when nuts are ingested. In this study the investigators launch and perform double-blind placebo-controlled nut challenges and oral desensitization/ protocol to those with serious symptoms in the challenge. The efficacy and safety of the new oral desensitization program is the primary outcome. The effect of oral desensitization on bronchial hyperreactivity, eosinophilic airway inflammation, and quality of life are secondary outcomes.