Study Status: Completed
Recruit Status: Completed
Study Type: Interventional
Official Title: Effects Of Oral Alfacalcidol On Maturation Of Dendritic Cells In Graves' Disease Patients
Brief Summary: Maturity level of dendritic cells (DC) plays a pivotal role in initiating and regulating autoimmunity. In Graves' disease (GD), DCs have more active immune responses than those in healthy subjects. Our previous study demonstrated immunoregulatory effects of in vitro 1,25-D3 on maturation of DC in GD patients. This study aims to evaluate the effect of oral 1α-D3 on DC maturation in GD patients.