Clinical Trial: Investigation Into the Infectivity Levels of Human Papilloma Virus (HPV) in Tonsillar Tissue

Study Status: Enrolling by invitation
Recruit Status: Enrolling by invitation
Study Type: Observational




Official Title: Investigation Into the Infectivity Levels of Human Papilloma Virus (HPV) in Tonsillar Tissue

Brief Summary:

Human Papilloma Virus (HPV) has been shown to be a cause of Head & Neck Squamous Cell Carcinoma (HNSCC) and the majority of current studies focus on what is happening in patients with a HPV HNSCC. But there is limited investigation into HPV infection in the oropharynx of patients who do not have HNSCC. The current incidence of oral HPV infection is not known in the general population locally and there is also limited information on what particular localities within the mouth that patients' harbour HPV infection what strains are present and if there are any differences in viral load.

Therefore the aim of this project is to investigate within patients that undergo tonsillectomies the rate of HPV infection in tonsils to determine the amount of HPV present within the community.