Clinical Trial: Hypertonic Saline With Dextran for Treating Hypovolemic Shock and Severe Brain Injury

Study Status: Completed
Recruit Status: Completed
Study Type: Interventional




Official Title: Effect of Hypertonic Resuscitation for Blunt Trauma

Brief Summary: The purpose of this study is to evaluate the clinical outcome of patients following blunt traumatic injury with hypovolemic shock, who receive either lactated ringer's solution or hypertonic saline with dextran (HSD) resuscitation; also, to focus specifically on neurologic outcome in patients with brain injury and on the effect of HSD resuscitation on inflammatory cell responsiveness.